CHARACTERISTICS OF OXYMETHOLONE OXYMETHOLONE
Oxymetholone (also known as Anapolon) is a potent synthetic anabolic steroid developed by Syntex Pharmaceuticals in the 1960s. Anapolon was originally developed to treat osteoporosis and anemia and to stimulate muscle growth in malnourished and weakened patients. The FDA approved the use of oxymetholone in humans. Later, non-steroidal drugs were developed to effectively treat anemia and osteoporosis, so the popularity of anapolone declined and in 1993, Syntex, like other manufacturers, decided to discontinue its production. However, oxymetholone remained in medicine as new research showed that anapolone was effective in treating HIV-infected patients.
Steroidal profile:
- Anabolic activity: 320%.
- Androgenic activity: 45%.
- Estrogenic activity: none, but estrogenic activity.
- Progestagenic activity: very low.
- Hepatic toxicity: high
- Oral use: oral (tablets)
- Decrease in HPTA function (own production of testosterone): Yes
- Half-life: 8-9 hours
- Duration of action: 15 hours
- Detection time: up to 8 weeks
Effects of Anadrol
Dramatic increase in muscle mass (Oxymetholone is considered one of the most effective bodybuilding steroids for muscle mass gain – up to 15 kg of muscle mass can be gained in one course of treatment with a significant rebound effect – up to 30% of the mass gained can be lost after the treatment is completed, as part of the mass gain is due to fluid accumulation).
Anapolon relieves joint pain and improves joint function (by retaining fluid and increasing synovial fluid production). However, not all athletes are aware of these benefits. It reduces the binding of sex hormones, which when combined with other anabolic hormones (such as testosterone), increases and accelerates the effects.
DOSAGE OF OXYMETHOLONE
Dosage form: 50 mg tablets
Dosage: men 50-150 mg/day women 50 mg/day
Anapolon is suitable for men over 21 years of age for intense growth of muscle mass. The duration of treatment with oxymetholone is 4-6 weeks. A treatment of more than 6 weeks should not be used, partly because the best results are obtained during the first three weeks, and partly because of possible liver toxicity. The maximum easily tolerated dose of Anapolon is 100 mg/day. This is firstly because higher doses have been shown not to lead to better results[8] and secondly because of the increased risk of adverse effects associated with Anapolon. For beginners, the optimal dose is 50 mg/day.
However, there are several dosing regimens with daily doses up to 200 mg. Gradually increasing the dose only makes sense if tolerance is a concern. The drug is usually taken at a fixed dose from the first to the last day of treatment. Tapering doses does not make practical sense.
Side effects
Anadrol is not suitable for older athletes because they are more susceptible to various side effects. In addition, they are at particular risk of liver damage and prostate carcinoma. Combined with a high-calorie and unfortunately often high-fat diet, the usual muscle-building diet can lead to an increase in blood cholesterol levels, an increase in LDL and a decrease in HDL. Natural testosterone production is greatly reduced as anapolone has an inhibitory effect on the hypothalamus, reducing or preventing the secretion of testicular gonadotropic hormone. At the beginning of treatment with Anapolone.
We advise women not to take Anapolone 50 because “Anapolone is simply too strong for the female body. However, some participants in national and international competitions take Anapolone and achieve great success. While we are aware of all the androgenic side effects of Anapolone, we must be careful when using it at 25 mg/day.
Due to several side effects (Oxymytolone) periodic liver monitoring is necessary. Some patients have iron deficiency in the blood. In this case, continuous biochemical monitoring of the blood for the presence of iron in it is recommended. In case of iron deficiency, this element should be used with great caution in patients with heart, liver or kidney disease. In the case of oedema, treatment should be combined with diuretics and/or manual treatment. If hypercalcaemia occurs, treatment should be stopped. Anabolic steroids may alter blood sugar level.
Diabetic patients should therefore be carefully monitored by a physician. Patients with prostate disease and enlargement should be treated very carefully. This drug can alter the balance of cholesterol in the body; it should be used with caution in patients with venereal disease, myocardial infarction, coronary heart disease. Therapy should be tailored to the cholesterol balance. In extremely rare cases, prolonged use of the drug can cause severe liver damage and theoretically even lead to the death of the patient, which in principle is very unlikely. leukemia, masculinity in women, pellosis of the liver. This medicinal product contains lactose. There are cases of intolerance in children and adolescents. The low lactose content is probably not the cause of this intolerance. A doctor should be consulted if diarrhoea occurs.
Anabolic steroids may increase sensitivity to drugs that reduce blood clotting. In this case, their dose is reduced. Sometimes jaundice, increased bilirubin, alkaline phosphate and transaminase values in the blood are observed. These values return to normal after discontinuation of treatment. Decreased testicular function has been observed in men. In women, purely male characteristics may be found: low and hoarse voice, changes in libido and irregular menstruation.
Other side effects of anabolic therapy include diarrhoea, drowsiness, cramps, nausea, irritability and hyperexcitability, tremors, low and hoarse voice, changes in libido and menstrual disorders. Other side effects of anabolic therapy include diarrhea, drowsiness, cramps, nausea, irritability and hyperexcitability, tremors. Other side effects of anabolic therapy include diarrhea, drowsiness, cramps, nausea, irritability and hyperirritability, chills.